In vitro and in vivo evaluation of efficacy and safety of Weizmannia coagulans HOM5301 for boosting immunity

Shiqi Zhang,Di Zhang,Tingting Wang,Suwon Lee,Chongyoon Lim,Yaxin Zhao,Pinglan Li

JOURNAL OF FUNCTIONAL FOODS（2023）

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摘要

•The complete genome sequence of W. coagulans HOM5301 was assembled and analyzed.•W. coagulans HOM5301 showed goodinvitroprobioticcharacteristics.•Daily treatment with W. coagulans HOM5301 spores boosted immunity in mice.•W. coagulans HOM5301 positively modulated the gut microbiota in mice.

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关键词

Weizmannia coagulans,Probiotics,Immunomodulation,Gut microbiota,Safety

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