A grade iii severe hypersensitivity caused by gadopentatic acid injection: a case report

istration, the patient developed skin itching. No obvious rash was found, but a 10 mg intravenous injection of dexamethasone was given. Recount of events: After 1 minute, skin pruritus had not improved significantly, saliva secretion had increased signifi-cantly, and a general discomfort appeared. At 12:10 PM, outside the scanning room, the patient suddenly became unconscious; 1 mg of EPINEPHrine was injected intramuscularly, and oxygen was given through a mask. Heart rate, blood pressure, and oxygen saturation steadily dropped. The patient was transferred to the intensive care unit. After EPINEPHrine, norepinephrine, terlipressin, and dexamethasone treatments, the vital signs eventually stabilized. The patient was judged to have had a grade III severe allergic reaction according to the first aid guidelines for severe allergic reactions in China. The patient was discharged from the hospital on the morning of January 14. Conclusion: This case stresses the importance of being equipped with the medicines, items, supplies, and equipment needed for emergency treatments in all departments where contrast agents are used. Patients with apparently mild adverse reactions to contrast agents should not be overlooked.