BRAF Mutation Heterogeneity Detected Using Circulating Tumor DNA Sequencing in Synchronous Colon Cancer: A Case Report.

Haruka Kono,Taro Yamanaka,Yuki Nishihara,Kenji Tomizawa,Rika Kizawa,Takeshi Yamaguchi,Yuko Tanabe,Shuichiro Matoba,Hiroya Kuroyanagi,Koichi Suyama,Yuji Miura

Cancer diagnosis & prognosis（2023）

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摘要

Genetic profiling with liquid biopsy at the time of recurrence and metastasis may be useful in patients with multiple synchronous cancers because there is less heterogeneity between primary and metastatic sites.

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关键词

circulating tumor dna,synchronous colon cancer,mutation,sequencing

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