Macrophages depletion alleviates lung injury by modulating AKT3/GXP4 following ventilator associated pneumonia.

Youfeng Zhu,Yang Chen,Di Xie, Dong Xia,Huanming Kuang,Xinmin Guo,Bo Ning

Frontiers in Immunology（2023）

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摘要

Collectively, this study suggests the need for further validation of the immunoregulatory function of AKT3 in lung cancer. Additionally, macrophage depletion mitigates lung injury by modulating the AKT3/GPX4 pathway in the context of VAP.

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lung injury,macrophages,akt3/gxp4

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