In low-risk penicillin allergies, direct oral challenge was noninferior to skin testing followed by oral challenge

Annals of Internal Medicine（2023）

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摘要

Copaescu AM, Vogrin S, James F, et al. Efficacy of a clinical decision rule to enable direct oral challenge in patients with low-risk penicillin allergy: the PALACE randomized clinical trial. JAMA Intern Med. 2023;183:944-952. 37459086.

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skin testing,oral challenge,direct oral challenge,low-risk

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