Mitochondrial energy metabolism correlates with an immunosuppressive tumor microenvironment and poor prognosis in esophageal squamous cell carcinoma.

Zewei Zhang,Gaowa Jin,Juan Zhao,Shuqin Deng, Feng Chen, Gaowa Wuyun,Lei Zhao,Quanfu Li

Computational and structural biotechnology journal（2023）

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摘要

MEM heterogeneity was observed in the immunosupressive TME of ESCC. Prognostic models based on MEM-related genes are helpful for screening early treatment patient groups and realizing personalized treatment. APOE and MAP1LC3A are potential target genes for the development of anti-ESCC drugs based on MEM-related genes.

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关键词

mitochondrial energy metabolism,immunosuppressive tumor microenvironment,squamous cell carcinoma

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