[Associations of cardiometabolic multimorbidity with grip strength and gait speed among older Chinese adults].

Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi(2023)

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Abstract
To investigate the associations of cardiometabolic multimorbidity (CMM) with grip strength and gait speed among older Chinese adults. This study included participants aged ≥60 years from the China Health and Retirement Longitudinal Survey during 2011-2015. Generalized estimating equation models were employed to estimate the associations of CMM with grip strength and gait speed. A total of 6 357 participants were included to measure grip strength and 6 250 participants to measure gait speed. Compared with no cardiometabolic disease, participants with 1 (=-0.018, 95%: -0.026--0.010), 2 (=-0.029, 95%: -0.041- -0.018), and ≥3 (=-0.050, 95%: -0.063- -0.037) cardiometabolic diseases were associated with a decreased grip strength. The associations between cardiometabolic disease counts (1: =-0.052, 95%: -0.3260.222; 2: =-0.083, 95%: -0.5060.340; ≥3: =-0.186, 95%: -0.7300.358) and gait speed were not statistically significant. The predictive value of gait speed of the participants with 0, 1, 2, and ≥3 cardiometabolic diseases were found to be 1.98 (95%: 1.38-2.58), 1.93 (95%: 1.34-2.51), 1.89 (95%: 1.18-2.61), and 1.79 (95%: 1.10-2.48) m/s respectively, which was clinically significant for the magnitude of the decrease. Cardiometabolic combinations with a higher risk of decreased grip strength and gait speed mainly seen in diabetes. Cardiometabolic disease counts and combinations were associated with grip strength and gait speed. Grip strength and gait speed can be used to measure CMM severity.
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Key words
cardiometabolic multimorbidity,grip strength,older chinese adults
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