血清miR-21-3p检测联合淋巴结粗针穿刺活检对甲状腺癌颈淋巴结转移的诊断价值
Journal of Bengbu Medical College(2023)
Abstract
目的:探讨血清miR-21-3p检测联合超声引导下淋巴结粗针穿刺活检(LCNB)对甲状腺癌颈淋巴结转移的诊断价值.方法:选取甲状腺癌伴颈淋巴结肿大(均行血清miR-21-3p检测及LCNB)病人 80 例,以手术病理为标准,比较血清miR-21-3p检测、超声引导下LCNB及两者联合检查对甲状腺癌伴颈淋巴结转移的诊断价值.结果:80 例病人经手术病理检查,有淋巴结转移者49 例,无转移者31 例.血清miR-21-3p检测联合超声引导下LCNB诊断甲状腺癌伴颈淋巴结转移准确度为91.8%、灵敏度为87.6%,均高于两者独立检查准确度76.2%、84.7%和灵敏度82.3%、85.7%(P<0.05),联合检查受试者工作曲线下面积为0.907 1,大于两者单独检测的0.776 5、0.829 2(P<0.05).结论:相较于单独检测,血清miR-21-3p联合超声引导下LCNB诊断甲状腺癌淋巴结转移的准确度、灵敏度更好,诊断效能更高.
MoreKey words
thyroid neoplasms,secondary carcinoma of lymph node,lymph node biopsy,miR-21-3p
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