Intratumoral CD103 + CD8 + T cells predict response to neoadjuvant chemoimmunotherapy in advanced head and neck squamous cell carcinoma.

Siqi Ren,Tianjun Lan,Fan Wu,Suling Chen,Xue Jiang,Chuying Huo,Zitian Li,Shule Xie,Donghui Wu,Ruixin Wang,Yanyan Li,Lin Qiu, Guoxin Huang,Shurui Li,Xiaojuan Wang,Meifeng Cen,Tingting Cai,Zhaoyu Lin,Jinsong Li,Bowen Li

Cancer communications (London, England)（2023）

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摘要

Our study highlights the impact of intratumoral CD103 CD8 TILs density on NACI efficacy in different cancers, while the efforts to elevate its population warrant further clinical investigation.

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关键词

CD103, CD8, head and neck squamous cell carcinoma, neoadjuvant chemoimmunotherapy, predictive marker, tumor-infiltrating lymphocyte

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