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Ultra-early rt-PA administration should improve patient outcome on mechanical thrombectomy: Post hoc analysis of SKIP.

Junya Aoki,Kentaro Suzuki,Yuki Sakamoto,Yuji Matsumaru,Masataka Takeuchi,Masafumi Morimoto,Ryuzaburo Kanazawa,Yohei Takayama,Yuki Kamiya,Keigo Shigeta,Seiji Okubo,Mikito Hayakawa,Norihiro Ishii,Yorio Koguchi,Tomoji Takigawa,Masato Inoue,Hiromichi Naito,Takahiro Ota,Teruyuki Hirano,Noriyuki Kato,Toshihiro Ueda,Yasuyuki Iguchi,Kazunori Akaji,Wataro Tsuruta,Kazunori Miki,Shigeru Fujimoto,Tetsuhiro Higashida,Mitsuhiro Iwasaki,Takuya Kanamaru,Tomonari Saito,Takehiro Katano,Akihito Kutsuna,Yasuhiro Nishiyama,Toshiaki Otsuka,Kazumi Kimura

Journal of the neurological sciences（2023）

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Abstract
Ultra-early rt-PA administration should improve patient outcomes on mechanical thrombectomy among patients with LVO. Relatively late rt-PA administration might increase the frequency of any ICH.
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Key words
mechanical thrombectomy,patient outcome,ultra-early
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