Differential Proteome Profiling Analysis under Pesticide Stress by the Use of a Nano-UHPLC-MS/MS Untargeted Proteomic-Based Approach on a 3D-Developed Neurospheroid Model: Identification of Protein Interactions, Prognostic Biomarkers, and Potential Therapeutic Targets in Human IDH Mutant High-Grade Gliomas.

Kaouthar Louati,Amina Maalej,Fatma Kolsi,Rim Kallel,Yassine Gdoura,Mahdi Borni, Leila Sellami Hakim,Rania Zribi,Sirine Choura,Sami Sayadi,Mohamed Chamkha,Basma Mnif,Zouheir Khemakhem,Tahya Sellami Boudawara,Mohamed Zaher Boudawara,Fathi Safta

Journal of Proteome Research（2023）

引用 2|浏览15

关键词

nanoflow UHPLC,tandem mass spectrometry (MS/MS),proteomics,grade-IV astrocytomas IDH mutant,3D neurospheroids,PPI networks,apoptogenic pathways,neurotoxicity,bioinformatic analysis,geneontology

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