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Macrophage susceptibility to infection by Ghanaian Mycobacterium tuberculosis complex lineages 4 and 5 varies with self-reported ethnicity.

Stephen Osei-Wusu,John K A Tetteh,Abdul Basit Musah,Desmond Opoku Ntiamoah,Nelly Arthur,Abraham Adjei,Ainhoa Arbues,Ebenezer Addo Ofori, Kwadwo Akyea Mensah,Sutaya Elsie Afua Galevo,Abena Frema Frempong,Prince Asare,Adwoa Asante-Poku,Isaac Darko Otchere,Kwadwo Asamoah Kusi, Tobias L Lenz,Sebastien Gagneux,Damien Portevin,Dorothy Yeboah-Manu

Frontiers in cellular and infection microbiology（2023）

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Abstract
Our results suggest that host ethnicity (driven by host genetic diversity), MTBC genetic diversity, and individual TB infection history are all acting together to modulate the outcome of macrophage infections by MTBC.
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Key words
ghanaian mycobacterium tuberculosis,macrophage susceptibility,infection,self-reported
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