Bidirectional relationship between nonalcoholic fatty liver disease and serum creatinine-to-body weight ratio as a proxy for skeletal muscle mass index.

Chao Tong,Aheyeerke Halengbieke,Xuetong Ni,Yumei Han,Lixin Tao,Deqiang Zheng,Qiang Li,Xinghua Yang

Journal of gastroenterology and hepatology（2023）

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摘要

This study indicated mutual causality between sCr/bw and NAFLD. Considering that sCr/bw is a surrogate marker of muscle mass index, the findings emphasize that NAFLD and low muscle mass form a vicious cycle, which should be taken seriously in clinical practice.

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关键词

Cohort study, Longitudinal study, Nonalcoholic fatty liver disease, Random intercept cross-lagged panel model, Serum creatinine-to-body weight ratio, Skeletal muscle mass index

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