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Expansion of Invasive Group A Streptococcus M1UK Lineage in Active Bacterial Core Surveillance, United States, 2019-2021

Yuan Li,Joy Rivers,Saundra Mathis,Zhongya Li,Sopio Chochua,Benjamin J. Metcalf,Bernard Beall,Jennifer Onukwube,Christopher J. Gregory,Lesley Mcgee

EMERGING INFECTIOUS DISEASES（2023）

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Abstract
From 2015-2018 to 2019. 2021, hypertoxigenic M1(UK) lineage among invasive group A Streptococcus increased in the United States (1.7%, 21/1,230 to 11%, 65/603; p<0.001). M1(UK) was observed in 9 of 10 states, concentrated in Georgia (n = 41), Tennessee (n = 13), and New York (n = 13). Genomic cluster analysis indicated recent expansions.
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Key words
active bacterial core surveillance,invasive
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