Trough ganciclovir concentration as predictor of leukopenia in lung transplant recipients receiving valganciclovir prophylaxis.

Transplant infectious disease : an official journal of the Transplantation Society(2023)

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摘要
These results suggest that higher ganciclovir trough concentrations are associated with an increased risk of leukopenia grade 3 or higher, and that creatinine clearance and lung re-transplantation affected the pharmacokinetics of ganciclovir.
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关键词
Cytomegalovirus, ganciclovir, lung transplantation, prophylaxis, therapeutic drug monitoring, valganciclovir
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