Abiraterone-Induced Hypokalemia: A Case Report

Bernard I. Nkwocha, Meenu Singh

Cureus(2023)

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Abstract
Abiraterone, an androgen biosynthesis inhibitor drug approved by the Food and Drug Administration (FDA) in 2011 for the treatment of metastatic prostate cancer, has seen an increase in prescriptions over the years, owing largely to the aging population and the association of prostate cancer with increasing age. As the rate of abiraterone prescription increases, it is important for physicians to be aware of its adverse effects profile to improve patient outcomes. This case report explains the mechanism, clinical presentation, and management of abiraterone-induced hypokalemia in a 67-year-old male with prostate cancer and highlights the importance of close monitoring and management of electrolyte levels for patients on abiraterone.
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Key words
urologic oncology, hypokalemia, abiraterone-induced hypokalemia, electrolyte imbalance, androgen-deprivation therapy, abiraterone, prostate cancer (pca), castration-resistant metastatic prostate cancer
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