The protective role of phosphodiesterase inhibitors in preventing colorectal cancer and advanced colorectal polyps: a systematic review and meta-analysis.
Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland（2023）
Abstract
Our study found a significant anticancer effect of PDE5i, as shown by a reduced risk of CRC in the context of both primary and secondary CRC prevention.
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Key words
chemoprevention, colorectal cancer, colorectal polyps, drug-repurposing, phosphodiesterase inhibitors
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