Severe Disease Burden and the Mitigation Strategy in the Arsenic-Exposed Population of Kaliprasad Village in Bhagalpur District of Bihar, India

Arun Kumar, Kanhaiya Kumar, Mohammad Ali,Vivek Raj, Abhinav Srivastava, Manishankar Kumar, Pintoo Kumar Niraj, Mukesh Kumar, Rishav Kumar,Dhruv Kumar,Akhouri Bishwapriya,Ranjit Kumar,Suresh Kumar,Gautam Anand,Santosh Kumar,Maiko Sakamoto, Ashok Kumar Ghosh

BIOLOGICAL TRACE ELEMENT RESEARCH(2024)

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摘要
The present study was carried out in the village Kaliprasad of Bhagalpur district of Bihar to know the arsenic exposure effect in the exposed population. A total of n = 102 households were studied, and their water and biological samples such as urine and hair were collected and analyzed in a graphite furnace atomic absorption spectrophotometer (GF-AAS). The assessment of arsenic-exposed village population reveals that the villagers were suffering from serious health-related problems such as skin manifestations (hyperkeratosis and melanosis in their palm and soles), breathlessness, general body weakness, mental disorders, diabetes, hypertension (raised blood pressure), hormonal imbalance, neurological disorders, and few cancer cases. About 77% of household hand pump water had arsenic level more than the WHO recommended level of 10 mu g/L, with highest level of 523 mu g/L. Moreover, in 60% individual's urine samples, arsenic concentration was very high with maximum 374 mu g/L while in hair 64% individuals had arsenic concentration above the permissible limit with maximum arsenic concentration of 11,398 mu g/kg. The hazard quotient (HQ) was also calculated to know the arsenic risk percentage in children as 87.11%, in females as 83.15%, and in males as 82.27% by groundwater. This has surpassed the threshold value of 1x10-6\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$1\times {10}<^>{-6}$$\end{document} for carcinogenic risk (CR) in children, female, and male population group in the village. Hence, the exposed population of Kaliprasad village are at very high risk of the disease burden.
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关键词
Groundwater arsenic contamination,Kaliprasad village,Public health assessment,Cancer risk assessment
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