Evaluación de la relación entre factores de riesgo cardiovascular, las lesiones endoscópicas de la papila renal y el tipo de litiasis renal

espanolIntroduccion y objetivos: Estudiar la relacion entre los factores de riesgo cardiovascular mas frecuentes con el tipo de lesion endoscopica de la papila renal y el tipo de litiasis renal. Material y metodos: Evaluamos prospectivamente 38 pacientes sometidos a cirugia intrarrenal retrograda (RIRS) analizando y clasificando el tipo de lesion observada en la papila renal (placa de Randall, Calcificacion intratubular y hendidura papilar). Posteriormente, se analiza el tipo de litiasis presente (oxalato calcico monohidrato, acido urico y litiasis de oxalato calcico dihidrato con o sin hidroxiapatita) y se recogen los factores de riesgo cardiovascular presentes (HTA, Diabetes Mellitus, Obesidad, Antecedentes de enfermedad cardiaca previa). Se realiza una comparacion de proporciones mediante el test de x2 con valor de significacion p Resultados: No se hallaron relaciones entre el tipo de factor de riesgo cardiovascular con el tipo de calcificacion papilar endoscopica. Se observo una tendencia a la presencia de calcificacion intratubular en pacientes obesos. La HTA y la Diabetes Mellitus se relacionaron con las litiasis de acido urico (p=0,025 y 0,005, respectivamente). La obesidad se relaciono con las litiasis de oxalato calcico dihidrato (p=0,023). Conclusiones: No parece existir una relacion entre los factores de riesgo cardiovascular y el tipo de calcificacion de la papila renal. A pesar de ello, se observa la tendencia de que pacientes con obesidad presentan una elevada frecuencia de calcificacion intratubular. Parece que existe una relacion entre las litiasis de acido urico en pacientes que padecen diabetes y/o HTA y entre las litiasis de oxalato calcico dihidrato con o sin hidroxiapatita en pacientes con obesidad. EnglishIntroduction and objetives: Study the relationship between the most frequent cardiovascular risk factors with the type of endoscopic injury of the renal papilla and the kind of renal lithiasis. Material and methods: We prospectively evaluated 38 patients undergoing retrograde intrarenal surgery (RIRS) by analyzing and classifying the type of injury observed in the renal papilla (Randall’s plaque, intratubular calcification and papillary cleft). Later, we analyzed the type of lithiasis present (calcium oxalate monohydrate, uric acid and calcium oxalate dihydrate lithiasis with or without hydroxyapatite) and the cardiovascular risk factors present (HTA, Diabetes Mellitus, Obesity, Historiy of previous heart disease). A proportional comparison was performed using the x2 test with significance value p Results: No relationship was found between the type of cardiovascular risk factor and the type of endoscopic papillary injury. Although, we find a tendency between the patients with obesity and the intratubular calcification. HTA and Diabetes Mellitus were related with uric acid stones (p = 0.025 and 0.005, respectively). Obesity was related with calcium oxalate dihydrate lithiasis (p = 0.023). Conclusions: There not seem to be a relationship between cardiovascular risk factors and the kind of renal papilla injury. In spite of , there is a tendency observed that correlated the patients with obesity with a high frequency of intratubular calcification. There seems to be a relationship between uric acid lithiasis in patients with diabetes or hypertension and another relationship between the calcium oxalate dihydrate lithiasis with or without hydroxyapatite and the patients with obesity.