Objective Comparison of Clinical and Cardiac Magnetic Resonance Biomarkers in Adolescents Presenting With Acute Chest Pain and Elevated Troponins Pre-COVID and Post-COVID Vaccination

Journal of Magnetic Resonance ImagingEarly View Letter to the Editor Objective Comparison of Clinical and Cardiac Magnetic Resonance Biomarkers in Adolescents Presenting With Acute Chest Pain and Elevated Troponins Pre-COVID and Post-COVID Vaccination Avanti Gulhane MD, DNB, Corresponding Author Avanti Gulhane MD, DNB [email protected] orcid.org/0000-0002-5264-951X Department of Cardiothoracic Radiology, University of Washington, Seattle, Washington, USA Address reprint requests to: A.G., 3235, 25th Ave W, Seattle, WA 98199, USA. E-mail: [email protected]Search for more papers by this authorBrian Soriano MD, Brian Soriano MD Department of Pediatric Cardiology, Seattle Children's Hospital, University of Washington, Seattle, Washington, USASearch for more papers by this authorLuana Stanescu MD, Luana Stanescu MD Department of Pediatric Radiology, University of Washington, Seattle, Washington, USASearch for more papers by this authorJenna Schauer MD, Jenna Schauer MD Department of Pediatric Cardiology, Seattle Children's Hospital, University of Washington, Seattle, Washington, USASearch for more papers by this authorMark Ferguson MD, Mark Ferguson MD Department of Pediatric Radiology, University of Washington, Seattle, Washington, USASearch for more papers by this authorErin Romberg MD, Erin Romberg MD Department of Radiology, Seattle Children's Hospital, University of Washington, Seattle, Washington, USASearch for more papers by this authorSadaf Bhutta MD, Sadaf Bhutta MD Department of Pediatric Radiology, University of Washington, Seattle, Washington, USASearch for more papers by this authorRandolph Otto MD, Randolph Otto MD Department of Radiology, Seattle Children's Hospital, University of Washington, Seattle, Washington, USASearch for more papers by this authorElizabeth Caris MD, Elizabeth Caris MD Department of Pediatric Cardiology, Seattle Children's Hospital, University of Washington, Seattle, Washington, USASearch for more papers by this authorSathish Mallenahalli MD, Sathish Mallenahalli MD Department of Pediatric Cardiology, Seattle Children's Hospital, University of Washington, Seattle, Washington, USASearch for more papers by this authorMichael Portman MD, Michael Portman MD Department of Pediatric Cardiology, Seattle Children's Hospital, University of Washington, Seattle, Washington, USASearch for more papers by this authorHarold Litt MD, PhD, Harold Litt MD, PhD Department of Radiology, Perelman School of Medicine of the University of Pennsylvania, Philadelphia, Pennsylvania, USASearch for more papers by this authorSujatha Buddhe MD, MSc, Sujatha Buddhe MD, MSc Department of Pediatric Cardiology, Seattle Children's Hospital, University of Washington, Seattle, Washington, USASearch for more papers by this author Avanti Gulhane MD, DNB, Corresponding Author Avanti Gulhane MD, DNB [email protected] orcid.org/0000-0002-5264-951X Department of Cardiothoracic Radiology, University of Washington, Seattle, Washington, USA Address reprint requests to: A.G., 3235, 25th Ave W, Seattle, WA 98199, USA. E-mail: [email protected]Search for more papers by this authorBrian Soriano MD, Brian Soriano MD Department of Pediatric Cardiology, Seattle Children's Hospital, University of Washington, Seattle, Washington, USASearch for more papers by this authorLuana Stanescu MD, Luana Stanescu MD Department of Pediatric Radiology, University of Washington, Seattle, Washington, USASearch for more papers by this authorJenna Schauer MD, Jenna Schauer MD Department of Pediatric Cardiology, Seattle Children's Hospital, University of Washington, Seattle, Washington, USASearch for more papers by this authorMark Ferguson MD, Mark Ferguson MD Department of Pediatric Radiology, University of Washington, Seattle, Washington, USASearch for more papers by this authorErin Romberg MD, Erin Romberg MD Department of Radiology, Seattle Children's Hospital, University of Washington, Seattle, Washington, USASearch for more papers by this authorSadaf Bhutta MD, Sadaf Bhutta MD Department of Pediatric Radiology, University of Washington, Seattle, Washington, USASearch for more papers by this authorRandolph Otto MD, Randolph Otto MD Department of Radiology, Seattle Children's Hospital, University of Washington, Seattle, Washington, USASearch for more papers by this authorElizabeth Caris MD, Elizabeth Caris MD Department of Pediatric Cardiology, Seattle Children's Hospital, University of Washington, Seattle, Washington, USASearch for more papers by this authorSathish Mallenahalli MD, Sathish Mallenahalli MD Department of Pediatric Cardiology, Seattle Children's Hospital, University of Washington, Seattle, Washington, USASearch for more papers by this authorMichael Portman MD, Michael Portman MD Department of Pediatric Cardiology, Seattle Children's Hospital, University of Washington, Seattle, Washington, USASearch for more papers by this authorHarold Litt MD, PhD, Harold Litt MD, PhD Department of Radiology, Perelman School of Medicine of the University of Pennsylvania, Philadelphia, Pennsylvania, USASearch for more papers by this authorSujatha Buddhe MD, MSc, Sujatha Buddhe MD, MSc Department of Pediatric Cardiology, Seattle Children's Hospital, University of Washington, Seattle, Washington, USASearch for more papers by this author First published: 25 August 2023 https://doi.org/10.1002/jmri.28971 Level of Evidence: 4 Technical Efficacy: Stage 3 Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat References 1Witberg G, Barda N, Hoss S, et al. Myocarditis after Covid-19 vaccination in a large health care organization. N Engl J Med 2021; 385(23): 2132-2139. 2Doeblin P, Jahnke C, Schneider M, et al. MR findings after COVID-19 and after COVID-19-vaccination—Same but different? Int J Cardiovasc Imaging 2022; 38(9): 2057-2071. 3Canter CE, Simpson KE. Diagnosis and treatment of myocarditis in children in the current era. Circulation 2014; 129(1): 115-128. 4Schauer J, Buddhe S, Gulhane A, et al. Persistent cardiac magnetic resonance imaging findings in a cohort of adolescents with post-coronavirus disease 2019 mRNA vaccine myopericarditis. J Pediatr 2022; 245: 233-237. 5Peng J, Zhao X, Zhao L, et al. Normal values of myocardial deformation assessed by cardiovascular magnetic resonance feature tracking in a healthy Chinese population: A multicenter study. Front Physiol 2018; 9: 1181. 6Bortolini MJS, Petriz B, Mineo JR, Resende RO. Why physical activity should be considered in clinical trials for COVID-19 vaccines: A focus on risk groups. Int J Environ Res Public Health 2022; 19(3): 1853. 7Ferreira VM, Schulz-Menger J, Holmvang G, et al. Cardiovascular magnetic resonance in nonischemic myocardial inflammation: Expert recommendations. J Am Coll Cardiol 2018; 72(24): 3158-3176. 8Malek LA, Kaminska H, Barczuk-Falecka M, et al. Children with acute myocarditis often have persistent subclinical changes as revealed by cardiac magnetic resonance. J Magn Reson Imaging 2020; 52(2): 488-496. 9Halushka MK, Vander Heide RS. Myocarditis is rare in COVID-19 autopsies: Cardiovascular findings across 277 postmortem examinations. Cardiovasc Pathol 2021; 50:107300. 10Jain SS, Steele JM, Fonseca B, et al. COVID-19 vaccination-associated myocarditis in adolescents. Pediatrics 2021; 148(5): e2021053427. 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