Doubling down to make killer T cells

Nature Immunology(2023)

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摘要
Control of the alternative commitment of immature CD4 + CD8 + T cells to the CD4 + or CD8 + lineage has long been the subject of intense scrutiny. A combination of CITE-seq and functional assays provides significant new insights into the distinct T cell antigen receptor signaling requirements for these lineage fates.
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关键词
Gene regulation in immune cells,Lymphopoiesis,T cells,Biomedicine,general,Immunology,Infectious Diseases
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