Steatotic liver disease as a new nomenclature for NAFLD from the perspectives of the MENA region: One size fits all this time

We read with interest the recently issued multi-society endorsement of the new nomenclature of what was formerly known as fatty liver disease, introducing the new terminology steatotic liver disease (SLD) as an overarching term encompassing different causes of steatosis. 1 Rinella M.E. Lazarus J.V. Ratziu V. Francque S.M. Sanyal A.J. Kanwal F. Romero D. Abdelmalek M.F. Anstee Q.M. Arab J.P. Arrese M. Bataller R. Beuers U. Boursier J. Bugianesi E. Byrne C. Castro Narro G.E. Chowdhury A. Cortez-Pinto H. Cryer D. Cusi K. El-Kassas M. Klein S. Eskridge W. Fan J. Gawrieh S. Guy C.D. Harrison S.A. Kim S.U. Koot B. Korenjak M. Kowdley K. Lacaille F. Loomba R. Mitchell-Thain R. Morgan T.R. Powell E. Roden M. Romero-Gómez M. Silva M. Singh S.P. Sookoian S.C. Spearman C.W. Tiniakos D. Valenti L. Vos M.B. Wai-Sun Wong V. Xanthakos S. Yilmaz Y. Younossi Z. Hobbs A. Villota-Rivas M. Newsome P.N. NAFLD Nomenclature consensus group. A multi-society Delphi consensus statement on new fatty liver disease nomenclature. J Hepatol. 2023 Jun 20; (S0168-8278(23)00418-X) (Epub ahead of print. PMID: 37364790)https://doi.org/10.1016/j.jhep.2023.06.003 Abstract Full Text Full Text PDF Google Scholar An essential criterion for a disease nomenclature to be widely and globally accepted is its generalizability and applicability in various geographical regions and its ability to consider and accommodate the heterogeneity among different social situations and stakeholders. In this letter, we aim to comment on the impact of the new nomenclature on managing the disease formerly known as NAFLD in our Middle East/North Africa (MENA) region. A multi-society Delphi consensus statement on new fatty liver disease nomenclatureJournal of HepatologyPreviewThe principal limitations of the terms nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) are the reliance on exclusionary confounder terms and the use of potentially stigmatising language. This study set out to determine if content experts and patient advocates were in favour of a change in nomenclature and/or definition. Full-Text PDF Open Access