Medical devices–associated biofilm infections and challenges in treatment

Biofilms are considered to be sessile communities that adhere on biotic and abiotic surfaces with the help of extracellular polymeric substances. These prevent the penetrance of antibiotics and other drugs resulting in the development of antibiotic or multidrug resistance organisms. In the field of health sectors, the use of medical devices is increasing rapidly; as a result, the enhanced hospital-associated infections are increasing at a rapid rate. The microbial cells tend to colonize on the surface of the medical devices, resulting in the development of various medical implant–associated infections. The position of the implantable medical devices regulates the type of colonization. The widespread use of medical devices, the biofilm act as a potent source for the development of various biofilm-associated nosocomial infections. This chapter would focus on various types of microbial species that are associated with the biomedical devices.