ID: 211449 Rapid Onset of Analgesia During Trial Period Utilizing Fast-Acting Sub-Perception Therapy SCS

Sub-perception Spinal Cord Stimulation (SCS) offers patients an opportunity to obtain pain relief without paresthesia. Onset of maximum pain relief using traditional sub-perception techniques (e.g., 1-10 kHz) can take up to several hours and even days to occur (unlike conventional paresthesia-based SCS), thereby prolonging and potentially compromising therapy optimization.1-3 Newly uncovered low frequency-based (90 Hz) Fast-Acting Sub-Perception Therapy (FAST) SCS is now often observed to provide pain relief below threshold of perception within seconds to minutes – a characteristic more analogous to traditional paresthesia-dependent SCS.4, 5 Obtaining a quick response to sub-perception therapies, especially during SCS trials, is key as it has the potential to determine expected response and provide customized therapies for effective pain relief. Here, we assessed the effectiveness and onset time of FAST during trial period in a multicenter observational case-series.