Comparison and Development Suggestions about Three Detection Methods for Tetrodotoxin

Tetrodotoxin poisoning cases are widely, frequently occurred by consuming noncompliant seafood such as puffer fish. Through extensively compare the existing detection method, 3 representative ways of detection method are elected. Mouse bioassay and ELISA belong to biological detection method, mass spectrometer and nuclear magnetic resonance, which belongs to Physical and chemical assay. We discuss the shortage of those method, compare the pros and cons with other method, and carry out some possible solutions to the current problems intended to provide reference for studies of the relevant area.