Determination of the Content of Paracetamol and Chlorphenamine Maleate in Feeling Better Cure Capsule
Guangzhou Chemical Industry(2014)
摘要
The sensitive content of paracetamol and maleic acid chlorobenzene in feeling better cure capsule was determined by HPLC. For XB- C18chromatographic column,methane alachol 0. 05 mol /L of potassium dihydrogen phosphate- triethylamine( 45∶55∶0. 02) adjusted pH value to 3. 4 with phosphoric acid as mobile phase and detection wavelength for 261 nm,the flow rate of 1. 0 mL /min,and column temperature 30 ℃. Acetaminophen in 30. 528 ~305. 28 μg /mL concentration range inside sex good,R2= 1,the average recovery was 98. 4%,RSD was 0. 68%. Maleic acid chlorobenzene that susceptibility in 24. 47~244. 74 μg /mL concentration range inside sex good,R2= 0. 9998,the average recovery was 95. 8%,and RSD% was 0. 75%. The method was simple,quick,accurate,and can effectively control the quality of the cure feeling better capsule.
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关键词
paracetamol,chlorphenamine maleate
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