Identification of key anti-inflammatory components of green prickly ash fruit based on zebrafish model and activity tracking strategy

Haiyang Wang, Ying Sun,Yonghong Xie,Fusheng Liu,Liwen Han

Journal of Functional Foods(2023)

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Abstract
•This study verified the activity of extracts and volatile oils separately.•This study was the first to verify the anti-inflammatory activity GPAF using a zebrafish model.•This study the first to identify the key anti-inflammatory active components of GPAF, Toddaline, Hydroxy-α-sanshool, and Hydroxy-β-sanshool.
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Key words
Green prickly ash fruit,Zebrafish,Dynamic molecular docking,Anti-inflammatory
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