Successful diagnosis of malignant lymphoma with endoscopic ultrasound-guided fine-needle biopsy for enlarged liver and spleen

A man in his 70s presented to a previous hospital with general malaise, night sweats, and anorexia. Blood tests revealed liver dysfunction, increased inflammatory response, and elevated serum Interleukin-2 receptor levels, raising the suspicion of malignant lymphoma. Computed tomography revealed hepatosplenomegaly, but no swollen lymph nodes suitable for biopsy were detected. The patient was referred to our department for a biopsy of the enlarged liver and spleen. Endoscopic ultrasound-guided fine-needle biopsy was performed on the enlarged liver and spleen, and the pathological results revealed diffuse large B-cell lymphoma. Subsequently, the patient was transferred to the Department of Hematology and chemotherapy was started.