Construction of Phenanthridinone Skeletons through Palladium-Catalyzed Annulation
JOURNAL OF ORGANIC CHEMISTRY(2023)
Abstract
Herein, a straightforward synthetic approach for the construction of phenanthridin-6-(5H)-one skeletons is disclosed. The developed protocol relies on palladium catalysis, providing controlled access to a range of functionalized phenanthridin-6-(5H)-ones in 59-88% yields. Furthermore, plausible reaction pathways are proposed based on mechanistic experiments.
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Key words
phenanthridinone skeletons,palladium-catalyzed
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