Circulating miR-146a predicts glucocorticoid response in thyroid eye disease.

Jacopo Manso,Simona Censi,Cristina Clausi,Ilaria Piva,Yi Hang Zhu,Alberto Mondin,Maria Chiara Pedron,Susi Barollo,Loris Bertazza,Giulia Midena,Raffaele Parrozzani,Caterina Mian

European thyroid journal（2023）

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摘要

This is the first study investigating the role of pre-treatment circulating miR-21 and miR-146a to predict responsiveness to GC in TED. miR-146a emerged as a simple, objective, new marker of GC sensitivity that could be used to avoid ineffective administration of GC therapy to TED patients.

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关键词

miR-146a, miR-21, thyroid eye disease, glucocorticoid sensitivity, glucocorticoid response, microRNA

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