Evaluation of therapeutic potential and anti-hyperchlostrolemic effects of prunes in albino rats: An experimental study

Ahad Mehmood,Mohsina Haq, Owais Ali,Muhammad Jaseem Khan,Noor Ullah, Aamir Ali Khan, Faheem Usman, Ayesha Asif,Farid S. Ataya,Dalia Fouad, Anwaar Iftikhar

PAKISTAN JOURNAL OF PHARMACEUTICAL SCIENCES(2023)

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Abstract
Hyperlipidemia is a global epidemic that causes various cardiovascular diseases (CVDs). Prunes include fiber and numerous phenolic compounds that decrease cholesterol by decreasing LDL oxidation and supporting heart health. This study examined the therapeutic effects of Prunus domestica prunes on plasma fatty acids in albino rats after ingesting prune pulp. After chemical examination, prunes were proximately examined for nutritional content. Prunus domestica pulp was given to hyperlipidemic rats for two months in a clinical trial. 12 albino rates and divide into 3 groups. First group was controlled, others experimental. The study's 15th, 30th, and 60th days evaluated lipid profile. The following study was analyzed using 2 way anova. Prunes have enough fiber, minerals, and polyphenols to affect hyperlipidemic rats. GIII rats lower LDL, weight, and HDL more than GI and GII.
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Key words
Low density lipids,weight loss,hyperlipidemia
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