The clinial and genetic charactheristics of retinoblastoma patients in a single center with four novel rb1 variants
International journal of ophthalmology(2023)
Abstract
Four novel variants are described and one of them is found in two different patients. This data is crucial for assessing prognosis. It serves as a guide for estimating the long-term risk of secondary malignancy as well as the short-term risk of developing additional malignancies in the same eye and the other eye.
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Key words
retinoblastoma patients,genetic characteristics
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