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The clinial and genetic charactheristics of retinoblastoma patients in a single center with four novel rb1 variants

International journal of ophthalmology(2023)

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Abstract
Four novel variants are described and one of them is found in two different patients. This data is crucial for assessing prognosis. It serves as a guide for estimating the long-term risk of secondary malignancy as well as the short-term risk of developing additional malignancies in the same eye and the other eye.
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Key words
retinoblastoma patients,genetic characteristics
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