Plasma AGE and Oxidation Products, Renal Function, and Preeclampsia in Pregnant Women with Type 1 Diabetes: A Prospective Observational Study.

Clare B Kelly,Harsha Karanchi,Jeremy Y Yu,Misti J Leyva,Alicia J Jenkins,Alison J Nankervis,Kristian F Hanssen,Satish K Garg,James A Scardo,Samar M Hammad,Christopher E Aston,Paul J Beisswenger,Timothy J Lyons

Journal of diabetes research（2023）

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摘要

Inverse associations of second and early third trimester plasma AGE with eGFR among type 1 diabetic women who developed PE suggest that these patients constitute a subset susceptible to AGE-mediated injury and thus to cardiorenal complications later in life. However, AGE/oxidation-P did not predict PE in type 1 diabetic women.

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关键词

preeclampsia,diabetes,renal function,plasma age,pregnant women

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