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NAFLD and nutraceuticals: a review of completed phase III and IV clinical trials.

Omar E Hegazi,Samer O Alalalmeh,Ghala Rashid Humaid Alnuaimi,Moyad Shahwan,Ammar Abdulrahman Jairoun,Nasser M Alorfi,Shaker A Majrashi,Mustfa Faisal Alkhanani, Abdullah Alkhattabi,Mansour M Alourfi,Faris A Alsolami,Saeed Alsharif, Hatim Alshahrani

Frontiers in medicine（2023）

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Abstract
This reveals a diverse range of nutraceuticals, with Omega-3 fatty acids and vitamin D being predominant in the management of NAFLD. The global distribution of trials highlights the widespread interest in these therapeutics. However, more rigorous, large-scale trials are needed to establish safety, efficacy, and optimal dosages.
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Key words
NAFLD, nutraceuticals, dietary supplements, Omega-3 fatty acids, vitamins
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