Efficacy of antiviral therapy and host-virus interactions visualised using serial liver sampling with fine-needle aspirates.

Samuel C Kim,Jeffrey J Wallin,Yanal Ghosheh,Muhammad Atif Zahoor,Juan Diego Sanchez Vasquez,Shirin Nkongolo,Scott Fung,Patricia Mendez,Jordan J Feld,Harry L A Janssen,Adam J Gehring

JHEP reports : innovation in hepatology（2023）

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摘要

Infection-dependent transcriptional changes and the impact of antiviral therapy on viral replication can be measured in longitudinal human liver biopsies using single-cell RNA sequencing data.

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关键词

Hepatitis B,Hepatocyte,Viral-Track,FNA,Fine needle aspirate,Liver

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