Outcomes of Tofacitinib Use in an Irish Pediatric Cohort.

Niamh Ryan,Sarah Cooper,Anna Dominik, Shoana Quinn,Annemarie Broderick,Billy Bourke,Séamus Hussey

JPGN reports（2023）

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摘要

Combining tofacitinib with other biologics is effective in select children with refractory UC. Early responders were more likely to achieve a sustained response at week 16. Failure to achieve remission by week 16 of tofacitinib therapy was strongly associated with progression to colectomy.

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关键词

tofacitinib use,pediatric

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