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The germline HLA-A02B62 supertype is associated with a PD-L1-positive tumour immune microenvironment and poor prognosis in stage I lung cancer

Ruijiang Lin, Xiaohua Chen,Fei Su, Hongbin Wang,Biao Han,Yanhui Chen, Cuixiang Zhang,Minjie Ma

Heliyon（2023）

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Abstract
The HLA-A02B62 supertype could serve as a possible indicator of poor prognosis in early-stage lung cancer. However, it may also act as a favorable prognostic factor for immunotherapy, given its association with a PD-L1-positive tumour microenvironment.
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Key words
HLA supertype,PD-L1,Tils,Prognosis,NSCLC
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