Predictive Factors for Efficacy of Oral Tacrolimus Induction Therapy in Moderate to Severe Ulcerative Colitis Patients: Large Multicenter Retrospective Cohort Study.

Naoki Oshima,Sakiko Hiraoka,Ryohei Hayashi,Sakuma Takahashi,Manabu Ishii,Shinichi Hashimoto,Kazuo Yashima,Shoko Igawa,Toshihiro Inokuchi,Yoshitaka Ueno,Tomoki Inaba,Hiroshi Matsumoto,Kousaku Kawashima,Taro Takami,Hajime Isomoto,Akiko Shiotani,Shinji Tanaka,Shunji Ishihara

Inflammatory bowel diseases（2023）

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摘要

Results of this multicenter study clearly indicate the efficacy of TAC induction therapy for patients with moderate to severe UC. Notably, previous or current use of anti-TNF-α antibodies was associated with poor achievement of clinical remission by week 12.

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