The causal effect of inflammatory bowel disease on diffuse large B-cell lymphoma: two-sample Mendelian randomization study.

Chuanyang Lu,Qiuni Chen,Hong Tao,Lei Xu,Jiaxin Li,Chunling Wang,Liang Yu

Frontiers in immunology（2023）

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摘要

The above MR study concluded that IBD itself is causally responsible for DLBCL, especially Crohn's disease. Further investigations are needed to elucidate the mechanism underlying this direct causal link.

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关键词

inflammatory bowel disease (IBD), diffuse large B-cell lymphoma (DLBCL), genome-wide association studies (GWAS), single-nucleotide polymorphisms (SNPs), Mendelian randomization (MR)

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