Increased blood CD226 - inflammatory monocytes with low antigen presenting potential correlate positively with severity of hemorrhagic fever with renal syndrome.

Kang Tang,Yongli Hou,Linfeng Cheng,Yusi Zhang,Juan Li,Qi Qin,Xuyang Zheng,Xiaozhou Jia,Chunmei Zhang,Ran Zhuang,Yun Zhang,Boquan Jin,Lihua Chen,Ying Ma

Annals of medicine（2023）

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摘要

CD226 iMOs increased during HTNV infection and the decrease in CD226 hampered the expression of HLA-DR/DP/DQ and CD80, which may promote the immune escape of HTNV and exacerbate clinical symptoms.

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关键词

Hantaan virus, hemorrhagic fever with renal syndrome, inflammatory monocyte, CD226, antigen presentation, >

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