Efficacy, safety, and tolerability of nivasorexant in adults with binge eating disorder: A randomized, Phase II proof of concept trial.

The International journal of eating disorders(2023)

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摘要
The results of this Phase II study indicate that nivasorexant was well tolerated in adults with BED, but did not improve binge eating behavior over placebo. Further research is needed to improve our understanding of the role of the orexin-1 receptor in BED.
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关键词
binge-eating disorder, clinical trial, orexin-1 receptor, Phase 2, proof-of-concept
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