Characterization and contribution of RPE senescence to Age-related macular degeneration in Tnfrsf10 knock out mice.

Iori Wada,Kenichiro Mori,Parameswaran G Sreekumar,Rui Ji,Christine Spee, Elise Hong,Keijiro Ishikawa,Koh-Hei Sonoda,Ram Kannan

bioRxiv : the preprint server for biology（2023）

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摘要

Our findings suggest that TNRSF10A is a regulator of regulates in RPE senescence. Further work on elucidating pathways of senescence will facilitate the development of new therapeutic targets for AMD.

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