Comparative Analysis of Molecular Pathogenic Mechanisms and Antiviral Development Targeting Old and New World Hantaviruses.

Arjit Vijey Jeyachandran,Joseph Ignatius Irudayam,Swati Dubey,Nikhil Chakravarty,Bindu Konda,Aayushi Shah,Baolong Su,Cheng Wang,Qi Cui,Kevin J Williams,Sonal Srikanth,Yanhong Shi,Arjun Deb,Robert Damoiseaux,Barry R Stripp,Arunachalam Ramaiah,Vaithilingaraja Arumugaswami

bioRxiv : the preprint server for biology（2023）

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摘要

Overall, our study describes advanced human PSC-derived model systems and systems-level transcriptomics and lipidomic data to better understand Old and New World hantaviral tropism, as well as drug candidates that can be further assessed for potential rapid deployment in the event of a pandemic.

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