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Comparative renal risk of long-term use of beta-lactams in combination with vancomycin across the continuum of care.

Lauren M Dolly,Christina G Rivera,Kelsey L Jensen,Kristin C Mara,Diana J Schreier,Abinash Virk,Kellie N Arensman Hannan

Therapeutic advances in infectious disease（2023）

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Abstract
Clinicians should exercise caution when using VPT for >2 weeks, including in the OPAT setting, even when no renal dysfunction is observed during the initial week of combination therapy.
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Key words
beta-lactams, nephrotoxicity, OPAT, vancomycin
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