Effect of caffeine on hippocampal memory and levels of gene expression in social isolation stress.

Seval Musuroglu Keloglan,Leyla Sahin,Sayad Kocahan,Ebru Annac,Nurhan Tirasci, Ayper Boga Pekmezekmek

International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience（2023）

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摘要

SI impaired spatial memory and causes morphological changes in adolescent rats, but this effect of isolation was not seen in Cf-treated animals. The effects of SI on NR2A, Cf on NR2B, and SNAP25 are remarkable. Here, we propose that the impaired effect of SI on spatial memory may be mediated by NR2A, but further studies are needed to explain this effect.

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