Association of apolipoproteins C-I and C-II truncations with coronary heart disease and progression of coronary artery calcium: Multi-Ethnic Study of Atherosclerosis.

Juraj Koska,Yueming Hu,Jeremy Furtado,Dean Billheimer,Dobrin Nedelkov,Matthew Allison,Matthew J Budoff,Robyn L McClelland,Peter Reaven

Atherosclerosis（2023）

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摘要

Increased apoC-II truncation was associated with reduced CHD, possibly explained by differences in lipid metabolism. Increased apoC-I and apoC-II truncations were also associated with less CAC progression and/or development of denser coronary plaques.

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关键词

Apolipoproteins,Lipids,Posttranslational proteoforms,Coronary artery calcium,Coronary heart disease

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