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The HIV-1 Nucleocapsid Regulates Its Own Condensation by Phase-Separated Activity-Enhancing Sequestration of the Viral Protease During Maturation

Sebastien Lyonnais,S. Kashif Sadiq,Cristina Lorca-Oro,Laure Dufau,Sara Nieto-Marquez,Tuixent Escriba,Natalia Gabrielli,Xiao Tan,Mohamed Ouizougun-Oubari,Josephine Okoronkwo,Michele Reboud-Ravaux,Jose Maria Gatell,Roland Marquet,Jean-Christophe Paillart,Andreas Meyerhans,Carine Tisne,Robert J. Gorelick,Gilles Mirambeau

Viruses（2021）

Cited 8|Views29
Key words
HIV-1,nucleocapsid,RNA,liquid-liquid phase separation,protease,molecular dynamics,atomic-force microscopy,biomolecular condensates,enzyme catalysis
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