Are we on track for diagnosing high-grade urothelial carcinoma with a minimum quantity of five malignant cells in lower tract specimens? Critical analysis of The Paris System Quantitation Criteria.
Cancer cytopathology（2023）
摘要
This study confirms that quantitation is an essential key to diagnose HGUC. The current TPS criterion of a minimum of five malignant cells in lower tract is robust with a ROHM of 100%. Diagnosing HGUC with less than five HGCs runs the risk of lowering the ROHM.
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关键词
false-positive urine cytology, high-grade cells (HGCs), high-grade urothelial carcinoma (HGUC), lower urinary tract, qualitative criteria, quantitation criteria, risk of high-grade malignancy (ROHM), The Paris System for Reporting Urinary Cytology (TPS), urine cytology
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