Pregnancy and long-term outcomes of female patients with chronic myeloid leukemia on tyrosine kinase inhibitors who experienced unplanned pregnancies

Leukemia research(2023)

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摘要
•High incidence of unplanned pregnancies noted in female chronic myeloid leukaemia patients on tyrosine kinase inhibitors.•Continuing imatinib during pregnancy may be a reasonable option for CML patients residing in low-and-middle-income countries.•Long-term disease progression is higher in patients with poorly controlled CML who discontinue therapy during pregnancy.•Patients without major molecular remission pre-and post-gestation require close monitoring for long-term disease progression.
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关键词
CML,CML-CP,DMR,ELN,LMICs,MMR,OS,PFS,TKI
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