Blood Lymphocyte Subsets and Proinflammatory Cytokine Profile in ROHHAD(NET) and non-ROHHAD(NET) Obese Individuals.

Daniela Fava,Fabio Morandi,Ignazia Prigione,Alessia Angelelli,Paola Bocca,Angela Pistorio,Stefano Volpi,Giuseppa Patti,Carlotta Pepino,Emilio Casalini,Anna Elsa Maria Allegri,Natascia Di Iorgi,Giuseppe d'Annunzio,Flavia Napoli,Mohamad Maghnie

Journal of the Endocrine Society（2023）

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摘要

Our findings contribute to support the hypothesis of immune dysregulation, which may underlie this complex, often fatal disease. Because ROHHAD(NET) syndrome is an ultra-rare disease, multicentric studies are needed to improve the effect of our data in the management of this condition.

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关键词

ROHHAD, ROHHAD-NET, immune phenotype, cytokines, chemokines

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